Epidemiological And Histopathologic Study Of Rhabdomyosarcoma cases in a tertiary Care hospital of Peshawar: Epidemiological and Histopathologic Study of Rhabdomyosarcoma Cases

Mohammad Manzoor; Bismah Ahmad; Adnan Sarwar; Mohibullah Khan; Inam-u llah; Hina Mir; Muhammad  Awais; Sudhair Abbas Bangash; Fares Muthanna

doi:10.54393/pbmj.v4i2.253

Authors

Mohammad Manzoor Pathology Department, Bacha Khan Medical College, Mardan
Bismah Ahmad Registrar Oral Pathology, CMH Lahore Medical College and Institute of Dentistry, Lahore
Adnan Sarwar Department of Pathology, Pak International Medical College, Peshawar
Mohibullah Khan Department of Histopathology, Pak International Medical College, Peshawar
Inam-u llah Department of Food Science, The University of Haripur, KPK, Pakistan
Hina Mir Department of Biochemistry, Shaheed Benazir Bhutto Women University, Peshawar
Muhammad Awais Department of Clinical Sciences, College of Veterinary and Animal Sciences, Jhang
Sudhair Abbas Bangash Faculty of Life Science, Department of Pharmacy, Sarhad University of Science and Information Technology, Peshawar
Fares Muthanna Department of Pharmaceutical Care, School of Pharmacy, Walailak University, Nakhon Si Thammarat, 80160, Thailand

DOI:

https://doi.org/10.54393/pbmj.v4i2.253

Keywords:

embryonal type, alveolar type, Peshawar, pleomorphic type – epidemiology, Rhabdomyosarcoma

Abstract

Aim: This study aimed to find out rhabdomyosarcoma’s (RMS) histopathological and immunohistochemical features. Settings: The current study was carried out at the Department of Pathology, Section of Histopathology, Khyber Teaching Hospital Peshawar. The study duration was between from 1st January 2015 to 30th of December 2020. Results: In the current study, all the 300 occurrences were found to be relevant. The most prevalent rhabdomyosarcoma was embryonal rhabdomyosarcoma (ERMS) (87.4%), followed by alveolar rhabdomyosarcoma (ARMS) (9.4%). In the current study we found that embryonal rhabdomyosarcomas was most frequent in males (64%). ERMS were 16.1 percent found in the genitourinary system followed by neck and head region (46.7%). Most samples displayed positive Desmin and MyoD1 immunohistochemistry staining. Conclusions: It is consistent with previously published rhabdomyosarcoma data from all across the globe that our patients' epidemiologic information and microscopic findings are consistent with one other.

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