Multi Drug Resistance Pseudomonas Aeruginosa Frequency and Antibiogram in A Tertiary Teaching Care Hospital in Pakistan

Frequency and Antibiogram of Pseudomonas aeruginosa


  • Syed Hasnain Ali Shah Department of Pharmacology, Kabir Medical College, Peshawar, Pakistan
  • Wajid Ali Department of Pharmacology, Ayub medical College, Abbottabad, Pakistan
  • Furqan Ali Shah Department of Pharmacology, Pak International Medical College, Peshawar, Pakistan
  • Shaikh Fahad Falah Department of Pharmacology, Khyber Girls Medical College, Peshawar, Pakistan
  • Erum Rehman Department of Pharmacology, Peshawar Medical and Dental College, Peshawar, Pakistan
  • Amna Umar Department of Pharmacology, Peshawar Medical and Dental College, Peshawar, Pakistan
  • Yumna Hidayat Department of Life Sciences, School of Science, University of Management and Technology, Lahore, Pakistan
  • Saira Afreen Department of Life Sciences, School of Science, University of Management and Technology, Lahore, Pakistan
  • Aayesha Riaz Department of Parasitology and Microbiology Faculty of Veterinary and Animal Sciences, PMAS Arid Agriculture University Rawalpindi
  • Irfan Ullah Department of Life Sciences, School of Science, University of Management and Technology, Lahore, Pakistan



Multi Drug Resistance, Pseudomonas aeruginosa, Antibiotics, Susceptibility, Resistance


Antibiotic usage and misuse increases the risk of developing bacteria that are resistant to treatment. A Gram-negative, aerobic bacillus called Pseudomonas aeruginosa is mostly responsible for nosocomial opportunistic infections. Objectives: To assess pathogen load and drug susceptibility profiles of Peshawar clinical specimens collected with MDR Pseudomonas aeruginosa isolates. Methods: Isolates were gathered from a variety of specimens, including pus, tracheal aspirate, swabs containing wound samples, fluids such as urine or blood, from department of microbiology hospital of Khyber teaching Peshawar. Clinical in-vitro study which were carried out at the Pharmacology Department, University of Peshawar. Kirby Bauer Disc diffusion method was used to identify the pattern of antibiotic susceptibility. Requirements of Clinical and Laboratory Standards Institute (2018) were followed for processing samples. Results: P. aeruginosa was found to be multidrug-resistant in about 56 percent of cases. The majority of the isolates (36.5%) were found in people between the ages of "60-80". Pus included the greatest percentage of MDR P. aeruginosa (34.2%), followed by tracheal aspiration (21.7 percent). Colistin had the highest sensitivity (100%) and was followed by ceftolozane/tazobactam (61 percent). With imipenem, the least sensitivity was noticed (20 percent). However, all anti-pseudomonal medications showed an increase in resistance. Conclusion: In our system, MDR P. aeruginosa infections are becoming more frequent. This threat can be avoided by prescribing antibiotics carefully. For the community to receive appropriate healthcare, regular lab identification and surveillance of this resistant pathogen is necessary


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DOI: 10.54393/pbmj.v5i7.667
Published: 2022-07-31

How to Cite

Ali Shah, S. H., Ali, W. ., Ali Shah, F. ., Fahad Falah, S. ., Rehman, E. ., Umar, A. ., Hidayat, Y. ., Afreen, S. ., Riaz, A. ., & Ullah, I. . (2022). Multi Drug Resistance Pseudomonas Aeruginosa Frequency and Antibiogram in A Tertiary Teaching Care Hospital in Pakistan: Frequency and Antibiogram of Pseudomonas aeruginosa . Pakistan BioMedical Journal, 5(7), 231–235.



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