Prediction of Fetal Gender Through Fetal Biometry

Fetal Gender Through Fetal Biometry

Abstract

An important part of prenatal care is gender determination, which shows expectant parents and medical professionals significant personal and medical insights. It becomes extremely important to determine early fetal gender for enhancing treatment approaches for sex-chromosome-related illnesses, like X-linked disorders. Objectives: To investigate the relationship between fetal gender determination during the second and third trimesters of pregnancy and ultrasound-based fetal biometric parameters, including estimated fetal weight (EFW), femur length (FL), abdominal circumference (AC), head circumference (HC), and biparietal diameter (BPD). Methods: This cross-sectional comparative study was conducted at the Radiology Department of Meer Khan Children and Family Hospital. Women between 14–40 weeks of gestation undergoing ultrasound for fetal assessment were included. Data were analyzed using SPSS version 26.0, applying an independent samples t-test and one-way ANOVA with a significance level set at p<0.05. The Shapiro-Wilk test was used in order to evaluate the data distribution normality. Results: The study found biometric ultrasound measurements of 125 fetuses (63 male and 62 female). Three important metrics showed higher values were found in male fetuses: Male had significantly higher FL (p=0.002, 95% CI: 3.16–14.28 mm). The test also indicated male with significantly higher AC, p=0.005, 95% CI: 10.77–58.44 mm, also significantly higher HC (p=0.016), 95% CI: 5.06–48.10 mm, in male was observed. Conclusions: Male fetuses had increased BPD and EFW compared to the female fetuses, whereas EFW and BPD showed non-significant trends toward higher values in male. Moreover, male fetuses have significantly greater AC, FL, and head circumference HC than female fetuses.