Nutritional and Potential Health Effect of Pumpkin seeds

Health Effect of Pumpkin seeds

Authors

  • Madiha Khan Niazi University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Farooq Hassan Hassan Punjab Healthcare Commission, Lahore, Pakistan
  • Syed Zahoor ul Hassan Zaidi Faculty of Eastern Medicine, Hamdard University, Karachi
  • Azka Afzal sahi University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Jawad Ashfaq Himayat e Islam Tibbia College, Lahore
  • Faiza Ejaz University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan
  • Zeerak Aamir Zeerak Matab Herbal and Hijama, Johar Town, Lahore
  • Sahar Imran University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pbmj.v5i6.515

Keywords:

Pumpkin seeds, Medicine, Anticancer, Antioxidant, Nutraceutical

Abstract

The Cucurbitaceae family's pumpkin seeds are often viewed as industrial waste and discarded. In many regions of the world, seeds are eaten raw, boiled, or roasted, but only for personal consumption. Because they are high in protein, fiber, minerals, and vitamins, they may be considered essential for the food industry. Because the seeds are a byproduct of the pumpkin fruit, they are less expensive, and their inclusion in a variety of foods may result in higher nutritious content at a lower cost. Pumpkin seeds have been found to be beneficial to one's health. More research and study on the transformation of these agro industrial waste products into valuable materials is most likely a huge step in the right direction for worldwide efforts in food sustainability.

References

Yang C, Wang B, Wang J, Xia S, Wu Y. Effect of pyrogallic acid (1, 2, 3-benzenetriol) polyphenol-protein covalent conjugation reaction degree on structure and antioxidant properties of pumpkin (Cucurbita sp.) seed protein isolate. Lwt. 2019 Jul 1;109:443-9. doi.10.1016/j.lwt.2019.04.034

Abou-Zeid SM, AbuBakr HO, Mohamed MA, El-Bahrawy A. Ameliorative effect of pumpkin seed oil against emamectin induced toxicity in mice. Biomed Pharmacother. 2018 Feb;98:242-251. doi: 10.1016/j.biopha.2017.12.040.

Amin MZ, Islam T, Uddin MR, Uddin MJ, Rahman MM, Satter MA. Comparative study on nutrient contents in the different parts of indigenous and hybrid varieties of pumpkin (Cucurbita maxima Linn.). Heliyon. 2019 Sep 13;5(9):e02462. doi: 10.1016/j.heliyon.2019.e02462

Pham TT, Tran TT, Ton NM, Le VV. Effects of pH and salt concentration on functional properties of pumpkin seed protein fractions. Journal of food processing and preservation. 2017 Aug;41(4):e13073. doi /10.1111/jfpp.13073

Jafari M, Goli SA, Rahimmalek M. The chemical composition of the seeds of Iranian pumpkin cultivars and physicochemical characteristics of the oil extract. European Journal of Lipid Science and Technology. 2012 Feb;114(2):161-7. :doi.10.1002/ejlt.201100102

Willhoft EM. Bread staling: I.-Experimental study. Journal of the Science of Food and Agriculture. 1971 Apr; 22(4):176-80..

doi.o10.1002/jsfa.2740220406

Broznić D, Čanadi Jurešić G, Milin Č. Involvement of α-, γ-and δ-tocopherol isomers from pumpkin (Cucurbita pepo L.) seed oil or oil mixtures in the biphasic DPPH disappearance kinetics. Food technology and biotechnology. 2016 Jun 24;54(2):200-10. doi.10.17113/ftb.54.02.16.4063

Naziri E, Mitić MN, Tsimidou MZ. Contribution of tocopherols and squalene to the oxidative stability of cold‐pressed pumkin seed oil (Cucurbita pepo L.). European Journal of Lipid Science and Technology. 2016 Jun;118(6):898-905. doi.10.1002/ejlt.201500261

Acorda JA, Mangubat IY, Divina BP. Evaluation of the in vivo efficacy of pumpkin (Cucurbita pepo) seeds against gastrointestinal helminths of chickens. Turkish Journal of Veterinary & Animal Sciences. 2019;43(2):206-11. doi.10.3906/vet-1807-39

Aghaei S, Nikzad H, Taghizadeh M, Tameh AA, Taherian A, Moravveji A. Protective effect of Pumpkin seed extract on sperm characteristics, biochemical parameters and epididymal histology in adult male rats treated with Cyclophosphamide. Andrologia. 2014 Oct;46(8):927-35. doi.10.1111/and.12175

Koh WY, Uthumporn U, Rosma A, Irfan AR, Park YH. Optimization of a fermented pumpkin-based beverage to improve Lactobacillus mali survival and α-glucosidase inhibitory activity: A response surface methodology approach. Food Science and Human Wellness. 2018 Mar 1;7(1):57-70. doi.10.1016/j.fshw.2017.11.001

Brogan DM, Mossialos E. A critical analysis of the review on antimicrobial resistance report and the infectious disease financing facility. Globalization and health. 2016 Dec;12(1):1-7. doi.10.1186/s12992-016-0147-y

Bharti SK, Kumar A, Sharma NK, Prakash O, Jaiswal SK, Krishnan T et al . Tocopherol from seeds of Cucurbita pepo against diabetes: Validation by in vivo experiments supported by computational docking. Journal of the Formosan Medical Association. 2013 Nov 1;112(11):676-90. doi.10.1016/j.jfma.2013.08.003

Sun J. Blaskovich MA, Jove R, Livingston SK, Coppola D, Sebti SM. Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity. Oncogene. 2005;24:3236-45. doi.10.1038/sj.onc.1208470

Vonk MM, Diks MA, Wagenaar L, Smit JJ, Pieters RH, Garssen J et al . Improved efficacy of oral immunotherapy using non-digestible oligosaccharides in a murine cow’s milk allergy model: a potential role for Foxp3+ regulatory T cells. Frontiers in immunology. 2017 Sep 29;8:1230. doi.org/10.1159/000350515

Plat J, Baumgartner S, Vanmierlo T, Lütjohann D, Calkins KL, Burrin DG et al . Plant-based sterols and stanols in health & disease:“Consequences of human development in a plant-based environment?”. Progress in lipid research. 2019 Apr 1;74:87-102.

Zhang L, Fan XR, Xie H, He QH, Nie YS, Zhang M et al . Anti-Inflammatory and antioxidant effects of kelong-capsule on testosterone-induced benign prostatic hyperplasia in rats. Evidence-Based Complementary and Alternative Medicine. 2018 Jun 26;2018. doi.10.1155/2018/5290514

Gohari AA, Farhoosh R, Haddad K. Chemical Composition And Physicochemical Properties Of Pumpkin Seeds (Cucurbita pepo Subsp. pepo Var. Styriaka) grown in Iran.

Gossell-Williams M, Davis A, O'connor N. Inhibition of testosterone-induced hyperplasia of the prostate of sprague-dawley rats by pumpkin seed oil. Journal of Medicinal Food. 2006 Jun 1;9(2):284-6. doi.10.1089/jmf.2006.9.284.

Hong H, Kim CS, Maeng S. Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutrition research and practice. 2009 Dec 1;3(4):323-7. doi.10.4162/nrp.2009.3.4.323

Xanthopoulou MN, Nomikos T, Fragopoulou E, Antonopoulou S. Antioxidant and lipoxygenase inhibitory activities of pumpkin seed extracts. Food Research International. 2009 Jun 1;42(5-6):641-6. doi.10.1016/j.foodres.2009.02.003

Lin KL, Lin JJ. Neurocritical care for anti-NMDA receptor encephalitis. biomedical journal. 2020 Jun 1;43(3):251-8. doi.10.1016/j.bjbas.2014.08.001

Hernández-Santos B, Rodríguez-Miranda J, Herman-Lara E, Torruco-Uco JG, Carmona-García R et al . Effect of oil extraction assisted by ultrasound on the physicochemical properties and fatty acid profile of pumpkin seed oil (Cucurbita pepo). Ultrasonics Sonochemistry. 2016 Jul 1;31:429-36. doi.10.1016/j.ultsonch.2016.01.029

Makni M, Fetoui H, Gargouri NK, Garoui EM, Jaber H, Makni J et al. Hypolipidemic and hepatoprotective effects of flax and pumpkin seed mixture rich in ω-3 and ω-6 fatty acids in hypercholesterolemic rats. Food and Chemical Toxicology. 2008 Dec 1;46(12):3714-20. doi.10.1016/j.fct.2008.09.057

Vetvicka V, Vetvickova J. Immune enhancing effects of WB365, a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts. North American journal of medical sciences. 2011 Jul;3(7):320. doi.10.4297/najms.2011.3411

Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. Journal of applied microbiology. 1999 Jun;86(6):985-90.

Cheong NE, Choi YO, Kim WY, Bae IS, Cho MJ, Hwang I et al . Purification and characterization of an antifungal PR-5 protein from pumpkin leaves. Molecules & Cells (Springer Science & Business Media BV). 1997 Apr 30;7(2).

Xie JM. Induced polarization effect of pumpkin protein on B16 cell. Fujian Med Univ Acta. 2004;38(4):394-5..

Park SC, Lee JR, Kim JY, Hwang I, Nah JW, Cheong H et al , a novel antifungal protein from pumpkin rinds. Biotechnology letters. 2010 Jan;32(1):125-30. doi.10.1007/s10529-009-0126-y

El-Mosallamy AE, Sleem AA, Abdel-Salam OM, Shaffie N, Kenawy SA. Antihypertensive and cardioprotective effects of pumpkin seed oil. Journal of Medicinal Food. 2012 Feb 1;15(2):180-9. doi.10.1089/jmf.2010.0299

Teugwa CM, Boudjeko T, Tchinda BT, Mejiato PC, Zofou D. Anti-hyperglycaemic globulins from selected Cucurbitaceae seeds used as antidiabetic medicinal plants in Africa. BMC complementary and alternative medicine. 2013 Dec;13(1):1-8. doi.10.1186/1472-6882-13-63

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Published

2022-06-30
CITATION
DOI: 10.54393/pbmj.v5i6.515
Published: 2022-06-30

How to Cite

Niazi, M. K., Hassan, F. H., Hassan Zaidi, S. . Z. ul ., Afzal sahi, A. ., Ashfaq, J. ., Ejaz, F. ., Aamir, Z. ., & Imran, S. (2022). Nutritional and Potential Health Effect of Pumpkin seeds: Health Effect of Pumpkin seeds. Pakistan BioMedical Journal, 5(6), 17–21. https://doi.org/10.54393/pbmj.v5i6.515

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