Impact of High-Intensity Exercise on Antioxidant System and Liver Enzymes

High-Intensity Exercise, Antioxidant System & Liver Enzymes


  • Alamgir Qureshi Punjab Univrsity
  • Muhammad Jamil University of Sindh, Jamshoro, Pakistan
  • Muhammad Zafar Iqbal Butt Department of Sports Sciences & Physical Education, University of the Punjab, Lahore, Pakistan
  • Shahzaman Khan IBA University, Sukhur
  • Nisar Ahmed Khaskheli IBA University, Sukhur
  • Muhammad Hashim Darya IBA University, Sukhur
  • Zeliha Selamoglu Nigde Ömer Halisdemir University, Nigde, Turkey
  • Betul Ozdemir Nigde Ömer Halisdemir University, Nigde, Turkey



High intensity exercise, Liver, Oxidative stress, FRAP Assay, ALT, ALP, AST


Liver is a vital organ of human body performing a variety of functions. In addition, maintenance of antioxidant system is also considered important. Objective: To observe the impact of high volume and high intensity exercise on blood redox state and enzymatic function of the liver. It was a comparative cross-sectional study conducted from January 2017 to Jan 2018 at Gomal University, Dera Ismail Khan Pakistan Methods: An observational study was conducted among twenty (40) voluntarily selected subjects. Measurement of both enzymatic functions of liver and blood redox state of the body were performed through liver functions tests (LFTS) and ferric reducing assay protocol (FRAP assay) by using blood samples collected from the subjects. Results: The collected data were analyzed through statistical package for social sciences (SPSS) version 25 by using different statistical tools such as Mean, Standard Deviation and T Score. Conclusions: Data analysis disclosed that high intensity exercise significantly affected the levels of ALT (t38= -4.369, p <0.05), ALP (t38= -.757, p >.05), AST (t38= -2.246, p < .05) and FRAP (t38=4.308, p<0.05).


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DOI: 10.54393/pbmj.v5i4.209
Published: 2022-04-30

How to Cite

Qureshi, A., Jamil, M. ., Butt, M. Z. I. ., Khan , S. ., Khaskheli , N. A. . ., Darya , M. H. ., Selamoglu, Z. ., & Ozdemir , B. . (2022). Impact of High-Intensity Exercise on Antioxidant System and Liver Enzymes : High-Intensity Exercise, Antioxidant System & Liver Enzymes . Pakistan BioMedical Journal, 5(4), 31–36.



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