Association of consanguineous marriages with congenital anomalies

Cousin marriages and birth defects

Authors

  • Maryam Naveed Faculty of Allied Health Sciences, University of Lahore, Lahore, Pakistan
  • Sajeeha Nadeem Faculty of Allied Health Sciences, University of Lahore, Lahore, Pakistan
  • Amber Hassan Faculty of Allied Health Sciences, University of Lahore, Lahore, Pakistan
  • Imrana Tanvir Department of Pathology, King Abdul Aziz Medical University, Jeddah, Saudi Arabia

DOI:

https://doi.org/10.52229/pbmj.v2i1.27

Abstract

Congenital anomalies are a major health problem all over the world; especially it is important cause of deaths and birth defects, chronic illness and disability in infants. The major cause of this is consanguineous marriages. Generation of cousin marriages have significant association with congenital anomalies Objective: To find out the association of consanguineous marriages with congenital anomaliespresent at the time of birthMethods:A cross sectional study was conducted at District Head Quarter Hospital, Okarafrom May to August, 2018. 100 adult individuals aged between 19 to 55 years, with and without cousin marriage of both genders were consecutively enrolled. Participants were assessed through pre-tested questionnaire, with prior written informed consent. Unwilling married individuals and individuals from other hospitals were not selected Results:According to resultsthere was a significant association between generation of cousin marriages with congenital anomalies present at the time of birth , as p value was 0.002Conclusions:Study concluded that the generation of cousin marriages has significant association with congenital anomalies present at the time of birth and due to cousin marriage 59% of the couples had congenital abnormalities in their children and 85% had genetic disorders.

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Published

2019-06-30
CITATION
DOI: 10.52229/pbmj.v2i1.27
Published: 2019-06-30

How to Cite

Naveed, M. ., Nadeem, S. ., Hassan, A. ., & Tanvir, I. . (2019). Association of consanguineous marriages with congenital anomalies: Cousin marriages and birth defects. Pakistan BioMedical Journal, 2(1). https://doi.org/10.52229/pbmj.v2i1.27

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